Inside Cellular Beauty: Joanna Ryglewicz on Smart Aging, Skin Energy, and the Future of Formulation
*INTERCELLULAR
*INTERCELLULAR
There’s something compelling about the way Joanna Ryglewicz approaches skincare. It’s not about chasing perfection, but about unlocking potential. As the founder of Oio Lab, Joanna has carved a space where deep science meets clean formulation, where curiosity drives innovation, and where every product begins with a question worth asking.
Her latest launch, the INTERCELLULAR Longevity Facial Serum, stems from a long-standing fascination with cellular health, inspired by thought leaders like David Sinclair and Peter Attia. It’s a formula developed over three years in her in-house lab, built around NAD⁺ pathways, epigenetic repair, and the idea that the skin, like the rest of the body, can be supported to function better for longer.
With INTERCELLULAR, Joanna isn’t trying to reverse time. She’s reframing how we move with it.
In this exclusive interview for Future of Skincare, Joanna opens up about the research behind the serum, the symbolism of sunflower sprouts, and what longevity really means in the context of modern beauty. Her answers reflect the same intention behind her work: grounded, intelligent, and refreshingly honest.
Keep reading for an in-depth look at the science, story, and vision behind one of the most thoughtful skincare launches of the year.
*An editorial born from a collaboration between Oio Lab and Future of Skincare.
What sparked the creation of INTERCELLULAR—and why now?
I’ve long been fascinated by the science of longevity—drawing from the work of pioneers like Dr. Peter Attia and Dr. David Sinclair, who are reshaping how we think about ageing. What began as curiosity quickly turned into a deep dive into healthspan—not just how long we live, but how well we live.
At Oio Lab, many ideas come from science, medicine, or ancestral traditions. When a theme keeps lighting me up, it usually finds its way into our formulas. That’s exactly how INTERCELLULAR Longevity Facial Serum was born.
I’ve never fully resonated with the term “anti-ageing”—even though I’ve used it. It never quite fit. With INTERCELLULAR, I wanted to shift the focus: how can we support the skin in maintaining its peak condition for longer? How do we preserve our best skin—not just for today, but for at least another decade?
That question led to over three years of research, formulation, and testing in our in-house laboratory. The result is a formula rooted in epigenetics and cellular energy—designed to activate the skin’s own potential. It’s not about changing the skin—it’s about helping it function at its best. Like you’ve slept well, eaten well, and spent time outside. Every day.
I’m deeply drawn to the idea of smart aging. It’s not about erasing time—it’s about showing up as yourself. Just freshening your face up, with all the stories it carries.
Why did you decide to center the formula around NAD+ and cellular longevity?
NAD⁺ is a coenzyme found in every living cell. It plays a vital role in energy production and cellular repair—essentially helping cells do what they’re meant to do efficiently. But as we age, our natural NAD⁺ levels decline, making it harder for the skin to renew itself.
I wanted to work with that process, not fight it. Supporting the skin at this energetic level felt like the most future-forward approach. We kept asking ourselves: how can we help the skin look its best, for longer?
That question led us to cellular longevity—and ultimately to INTERCELLULAR. A formula designed not just to treat the surface, but to energise the skin from within.
RejuveNAD™ is derived from sunflower sprouts—what drew you to this ingredient both scientifically and symbolically?
What drew me to RejuveNAD™ was the data. It’s a certified-organic, patented botanical extract from sunflower sprouts, grown in a controlled, soil-free environment using sustainable indoor farming methods. This process ensures purity, consistency, and minimal environmental impact—which aligns beautifully with our values at Oio Lab.
It works at the cellular level to help restore NAD⁺ and targets five of the biological hallmarks of ageing—like mitochondrial dysfunction and cellular senescence. These are the mechanisms that shape how skin ages over time.
Clinically, the results were equally compelling: smoother texture, reduced wrinkle depth, and skin that appeared up to 8.2 years younger in just six weeks. That kind of measurable performance, from a clean and plant-based ingredient, is exactly the kind of innovation we believe in.
And there’s symbolism too. Sunflowers naturally turn toward the light. That image stayed with me—of skin that isn’t resisting time, but quietly turning toward longevity. Toward life. Embracing transformation, not fighting change.
In a market full of anti-aging promises, what makes longevity skincare different—and more urgent?
I think longevity skincare reflects a deeper cultural shift. We’re starting to rethink what aging really means. What is beauty, really? How do we want to age—and how do we want to feel as we do it? These are very personal questions.
To some extent, the way you age is a choice. But it also reveals something deeper—about how we live and what we value.
Longevity skincare isn’t about reversing time—it’s about aligning with it. The urgency is now. In a world that pushes certain beauty standards, there’s power in asking: How do I want to age?
We wanted to offer a solution for people who seek to integrate modern science into a grounded approach to beauty—one that supports who we are becoming, without clinging to who we used to be. It’s not about pretending time isn’t passing. It’s about choosing how we walk with it.
How did you ensure that actives like RejuveNAD™, spermidine, and ozonated omegas worked in harmony—not just individually?
Skin longevity is a complex topic—and skin itself is a multi-layered organ. We knew from the start that supporting it effectively would require a multidimensional approach.
That’s why we combined RejuveNAD™ with a vegan collagen complex naturally rich in spermidine, to support cell renewal and improve elasticity; and our exclusive ozonated omega 3, 6, and 9 esters, to enhance absorption.
There's much more. We included ectoine, to help strengthen the skin barrier and pomegranate plant stem cells, to support radiance and a more even tone.
From the beginning, we tested not just individual performance, but how each ingredient works in synergy—ensuring they complement one another and amplify the overall effect. That’s essential to how we formulate.
What visible results can users expect—and when do they typically start to feel or see a shift in their skin?
You can expect to notice a difference right away. Just 30 minutes after the first application, instrumental tests showed a 36% increase in hydration^ and a 25% improvement in skin smoothness^. Skin looks more rested—like after a really good night’s sleep*.
After 7 days, 86% of users confirmed a visible improvement in their skin’s overall condition*.
And over time, those results build. After 28 days, we measured a 22% increase in firmness, a 9% reduction in wrinkle depth, and a visible boost in skin density^. In our in-use test, 70% of participants said their skin looked its best.*
It’s a formula that delivers both immediate glow and long-term support.
^Instrumental tests. *In-use test on 50 participants.
Who is INTERCELLULAR designed for? And how does it fit into a daily ritual—morning, evening, or both?
INTERCELLULAR is designed for anyone looking to renew and sustain their skin’s peak condition—helping it age smarter by visibly smoothing, firming, and enhancing its vitality, regardless of skin type.
It’s formulated with sustainably sourced, certified ingredients, and is free from synthetic fragrances and preservatives, making it suitable even for sensitive skin and the delicate eye area.
The texture is lightweight and milky, which makes it easy to layer—both morning and evening. I personally use 2–3 pumps after toner, followed by a cream or oil.
You describe the formula as communicating with the skin. What role does epigenetics play in that dialogue?
Epigenetics is about how external factors—like diet, lifestyle, or what we put on our skin—can influence how our genes express themselves. With INTERCELLULAR, we’re using advanced technology to maximise the chance of sending the right signals—ones that energise, renew, and strengthen. It’s about activating your skin’s potential.
What does “smart skin” mean to you—and how does INTERCELLULAR help unlock it?
To me, smart skin is your best skin—for longer. Ideally, for at least another decade. It’s about giving your skin the right support to help it stay healthy, balanced, and radiant.
INTERCELLULAR works across multiple dimensions—boosting hydration, strengthening resilience, and activating renewal at the cellular level. All to help your skin look and feel its best.
How do you personally define “aging well”—beyond the mirror?
For me, aging well means sustaining the inner sparks of curiosity. It’s noticing them, following them, and making more space for what makes you feel alive.
It’s also about continuously working on yourself—the quality of your thoughts, and getting to the root of them. For me, it’s a shift toward being gentler, less judgmental, and more tuned in to what makes me happy every day. Small things—but so important. In many ways, they shape how you age. It’s about not getting too rigid.
What’s one skincare ritual you consider sacred—and one beauty myth you’ve let go of?
For me, it’s all about consistency—and knowing exactly what you’re putting on your skin, and in what concentrations. When it comes to products, it’s all about the data. That’s what makes a difference over time.
As for rituals… they’re deeply individual. I’m results-oriented, and I live a fast-paced life where time matters. But I also understand that for some, skincare is more about relaxation than results—and that’s valid too. So I’ve let go of rigid rules.
Is there a book, thinker, or idea that’s shaped your vision of beauty, health, or time?
Definitely not just one. I tend to jump from one author to another, picking up the bits and pieces that resonate most in the moment. I like weaving ideas together—science, philosophy, biology, energy work. It’s more of an evolving patchwork than a single worldview, always filtered through my own lens.
If INTERCELLULAR had a soundtrack or scent—what would it evoke?
I think it would sound like a mix between Polo & Pan, the László soundtrack, and El Búho’s Floating Islands.
And the scent? Exactly as it is. It smells like our exclusive ozonated linseed oil—developed in-house by our scientists. You know it when you smell it.
What was the feeling when you first held the finished product in your hands?
Honestly? I thought—it looks even better than in the visualisations! (laughs)
I really love this product. I was happy with the journey it took to get there—the care, the decisions, the countless refinements.
I’m proud of my team and the way we stayed true to our standards. That feeling of integrity, of building something beautiful on our own terms... that’s what stayed with me.
What future are you building—through beauty, through science, through story?
A future where authenticity is recognised—and supported.
Through a journey of bold questions and learning from them.
Creating space for others—especially women—to grow, speak up, and bring forward ideas that are both intelligent and intuitive.
I want to build a future where you can have it all: nature and advanced technology. Where there is depth and play, scientific rigour and curiosity.
A future rooted in following what lights us up—supported by data, but not reduced to it.
A future that makes space for authenticity, intelligence, and a bright pop of colour.
